Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Superoxide Dismutase-Loaded Solid Lipid Nanoparticles Prepared by Cold Homogenization Method: Characterization and Permeation Study Through Burned Rat Skin

Masoud Ali Karami 1 , Behzad Sharif Makhmal Zadeh 1 , 2 , * , Maryam Koochak 1 and Eskandar Moghimipur 1
Authors Information
1 School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: November 2016, 11 (4); e33968
  • Published Online: October 8, 2016
  • Article Type: Research Article
  • Received: October 22, 2015
  • Revised: January 11, 2016
  • Accepted: September 14, 2016
  • DOI: 10.17795/jjnpp-33968

To Cite: Karami M A, Sharif Makhmal Zadeh B, Koochak M, Moghimipur E. Superoxide Dismutase-Loaded Solid Lipid Nanoparticles Prepared by Cold Homogenization Method: Characterization and Permeation Study Through Burned Rat Skin, Jundishapur J Nat Pharm Prod. 2016 ; 11(4):e33968. doi: 10.17795/jjnpp-33968.

Copyright © 2016, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Parihar A, Parihar MS, Milner S, Bhat S. Oxidative stress and anti-oxidative mobilization in burn injury. Burns. 2008; 34(1): 6-17[DOI][PubMed]
  • 2. Hettiaratchy S, Dziewulski P. ABC of burns: pathophysiology and types of burns. BMJ. 2004; 328(7453): 1427-9[DOI][PubMed]
  • 3. Latha B, Babu M. The involvement of free radicals in burn injury: a review. Burns. 2001; 27(4): 309-17[PubMed]
  • 4. Santos FX, Arroyo C, Garcia I, Blasco R, Obispo JM, Hamann C. Role of mast cells in the pathogenesis of postburn inflammatory response: reactive oxygen species as mast cell stimulators. Burns. 2000; 26: 145-7[DOI]
  • 5. Jadot G, Vaille A, Maldonado J, Vanelle P. Clinical pharmacokinetics and delivery of bovine superoxide dismutase. Clin Pharmacokinet. 1995; 28(1): 17-25[DOI][PubMed]
  • 6. Celik O, Akbuga J. Preparation of superoxide dismutase loaded chitosan microspheres: characterization and release studies. Eur J Pharm Biopharm. 2007; 66(1): 42-7[DOI][PubMed]
  • 7. Galovic Rengel R, Barisic K, Pavelic Z, Zanic Grubisic T, Cepelak I, Filipovic-Grcic J. High efficiency entrapment of superoxide dismutase into mucoadhesive chitosan-coated liposomes. Eur J Pharm Sci. 2002; 15(5): 441-8[PubMed]
  • 8. KarolaVorauer U, Eckhard F, Wagner A, Ferko B, Katinger H. Topically applied liposome encapsulated superoxide dismutase reduces postburn wound size and edema formation. EurJ Pharm Sci. 2001; 14: 63-7[DOI]
  • 9. Domínguez A. Modifying superoxide dismutase for improved biopharmaceutical properties. Biotecnologia Aplicada. 2006; 23: 17-21
  • 10. Shi F, Zhao JH, Liu Y, Wang Z, Zhang YT, Feng NP. Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil. Int J Nanomedicine. 2012; 7: 2033-43[DOI][PubMed]
  • 11. Ekambaram PA, Sathali A, Priyanka K. Solid Lipid Nanoparticles: A review. Sci Revs Chem Commun. 2012; 2(1): 80-102
  • 12. JS Khazi MI, Sharma NK, Hiremath SP, Makandi VG. Solid Lipid Nanoparticles: Methods of Preparation. Indian J Novel Drug Del. 2011; 3(3): 170-5
  • 13. Almeida AJ, Souto E. Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv Drug Deliv Rev. 2007; 59(6): 478-90[DOI][PubMed]
  • 14. Christine J, Weydert J, Joseph J. Measurement of superoxide dismutase, catalase, and glutathione peroxidase inculturedcellsandtissue. Cullen Nat Protoc. 2011;
  • 15. Mukherjee S, Ray S, Thakur RS. Solid lipid nanoparticles: a modern formulation approach in drug delivery system. Indian J Pharm Sci. 2009; 71(4): 349-58[DOI][PubMed]
  • 16. Wang Y, Gao JQ, Zheng CH, Xu DH, Liang WQ. Biodegradable and complexed microspheres used for sustained delivery and activity protection of SOD. J Biomed Mater Res B Appl Biomater. 2006; 79(1): 74-8[DOI][PubMed]
  • 17. Giovagnoli S, Blasi P, Ricci M, Rossi C. Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery. AAPS PharmSciTech. 2004; 5(4): 51[DOI][PubMed]
  • 18. Kigasawa K, Miyashita M, Kajimoto K, Kanamura K, Harashima H, Kogure K. Efficient intradermal delivery of superoxide dismutase using a combination of liposomes and iontophoresis for protection against UV-induced skin damage. Biol Pharm Bull. 2012; 35(5): 781-5[PubMed]
  • 19. Aburahma MH, Badr-Eldin SM. Compritol 888 ATO a multifunctional lipid excipients in drug delivery systems and nanopharmaceuticals. Expert Opin Drug Deliv. 2014; 11(12): 1865-83
  • 20. Jee JP, Lim SJ, Park JS, Kim CK. Stabilization of all-trans retinol by loading lipophilic antioxidants in solid lipid nanoparticles. Eur J Pharm Biopharm. 2006; 63(2): 134-9[DOI][PubMed]
  • 21. Kheradmandnia S, Vasheghani-Farahani E, Nosrati M, Atyabi F. Preparation and characterization of ketoprofen-loaded solid lipid nanoparticles made from beeswax and carnauba wax. Nanomedicine. 2010; 6(6): 753-9[DOI][PubMed]
  • 22. Madureira AR, Campos DA, Fonte P, Nunes S. Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid. RSC Adv. 2015; 5: 22665-73[DOI]
  • 23. Dash S, Murthy PN, Nath L, Chowdhury P. Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm-Drug Res. 2010; 67(3): 217-23
  • 24. Kajimoto K, Yamamoto M, Watanabe M, Kigasawa K, Kanamura K, Harashima H, et al. Noninvasive and persistent transfollicular drug delivery system using a combination of liposomes and iontophoresis. Int J Pharm. 2011; 403(1-2): 57-65[DOI][PubMed]
  • 25. Lasch J, Laub R, Wohlrab W. How deep do intact liposomes penetrate into human skin? J Control Rel. 1992; 18: 55-8[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments