Jundishapur Journal of Natural Pharmaceutical Products

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A Simple Method for Extraction and Purification of Hypericins from St John’s Wort

Zahra Ramezani 1 , * and Mitra Zamani 2
Authors Information
1 Department of Medicinal Chemistry, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Department of Chemistry, Faculty of Science, Ahvaz Branch of Azad University Science and Research Center, Ahvaz, Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: February 2017, 12 (1); e13864
  • Published Online: February 8, 2017
  • Article Type: Brief Report
  • Received: June 17, 2015
  • Revised: October 21, 2016
  • Accepted: December 4, 2016
  • DOI: 10.5812/jjnpp.13864

To Cite: Ramezani Z, Zamani M. A Simple Method for Extraction and Purification of Hypericins from St John’s Wort, Jundishapur J Nat Pharm Prod. 2017 ; 12(1):e13864. doi: 10.5812/jjnpp.13864.

Copyright © 2017, Jundishapur Journal of Natural Pharmaceutical Products. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results and Discussion
  • 1. Saddiqe Z, Naeem I, Maimoona A. A review of the antibacterial activity of Hypericum perforatum L. J Ethnopharmacol. 2010; 131(3): 511-21[DOI][PubMed]
  • 2. Tchakam PD, Lunga PK, Kowa TK, Lonfouo AH, Wabo HK, Tapondjou LA, et al. Antimicrobial and antioxidant activities of the extracts and compounds from the leaves of Psorospermum aurantiacum Engl. and Hypericum lanceolatum Lam. BMC Complement Altern Med. 2012; 12: 136[DOI][PubMed]
  • 3. Pakseresht S, Boustani H, Azemi ME, Nilsaz J, Babapour R, Haghdust MR. Evaluation of Pharmaceutical Products of St. John's Wort Efficacy Added on Tricyclic Antidepressants in treating Major Depressive Disorder: A Double Blind Randomized Control Trial. Jundishapur J Nat Pharm Prod. 2012; 7(3): 106-10[DOI][PubMed]
  • 4. Koul VK, Koul S. Process optimization for the extraction of hyperforin and hypericin from St. John’s Wort. Nat Prod Radiance. 2007; 6(4): 293-6
  • 5. Santos-Filho SD, Bernardo RM, Santos KCM, Fonseca AS, Bernardo-Filho M. Influence of an aqueous extract of Hypericum perforatum (Hypericin) on the survival of Escherichia coli AB1157 and on the electrophoretic mobility of pBSK plasmid DNA. Rev Bras Farmacogn. 2008; 18(3): 326-30[DOI]
  • 6. Liu FF, Ang CYW, Heinze TM, Rankin JD, Beger RD, Freeman JP, et al. Evaluation of major active components in St. John’s Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation. J Chromatogr A. 2000; 888(1-2): 85-92[DOI]
  • 7. Cossuta D, Vatai T, BÁThori M, Hohmann J, Keve T, SimÁNdi B. Extraction of hyperforin and hypericin from St. John's Wort (Hypericum Perforatum L.) with different solvents. J Food Process Eng. 2012; 35(2): 222-35[DOI]
  • 8. Li Z, Qin C, Li D, Hou Y, Li S, Sun J. Molecularly imprinted polymer for specific extraction of hypericin from Hypericum perforatum L. herbal extract. J Pharm Biomed Anal. 2014; 98: 210-20[DOI][PubMed]
  • 9. Ramezani Z, Aghel N, Keyghobadi H. Rutin from different parts of Capparis spinosa growing wild in Khuzestan/Iran. Pak J Biol Sci. 2008; 11(5): 768-72[DOI][PubMed]
  • 10. Aghel N, Ramezani Z, Beiranvand S. Hesperidin from Citrus sinensis cultivated in Dezful, Iran. Pak J Biol Sci. 2008; 11(20): 2451-3[DOI][PubMed]
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