Jundishapur Journal of Natural Pharmaceutical Products

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Berberis Fruit Extract and Biochemical Parameters in Patients With Type II Diabetes

Zolikha Moazezi 1 and Durdi Qujeq 2 , 3 , *
Authors Information
1 Department of Internal Medicine, Babol University of Medical Sciences, Babol, IR Iran
2 Cellular and Molecular Biology Research Center, Babol University of Medical Sciences, Babol, IR Iran
3 Department of Biochemistry and Biophysics, Babol University of Medical Sciences, Babol, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: May 3, 2014, 9 (2); e13490
  • Published Online: April 7, 2014
  • Article Type: Research Article
  • Received: July 9, 2013
  • Revised: January 5, 2014
  • Accepted: January 28, 2014
  • DOI: 10.17795/jjnpp-13490

To Cite: Moazezi Z, Qujeq D. Berberis Fruit Extract and Biochemical Parameters in Patients With Type II Diabetes, Jundishapur J Nat Pharm Prod. 2014 ; 9(2):e13490. doi: 10.17795/jjnpp-13490.

Abstract
Copyright © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Ford ES. Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care. 2005; 28(7): 1769-78[PubMed]
  • 2. Ravaglia G, Forti P, Maioli F, Bastagli L, Chiappelli M, Montesi F, et al. Metabolic Syndrome: prevalence and prediction of mortality in elderly individuals. Diabetes Care. 2006; 29(11): 2471-6[DOI][PubMed]
  • 3. Lee YS, Kim WS, Kim KH, Yoon MJ, Cho HJ, Shen Y, et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes. 2006; 55(8): 2256-64[DOI][PubMed]
  • 4. Ko BS, Choi SB, Park SK, Jang JS, Kim YE, Park S. Insulin sensitizing and insulinotropic action of berberine from Cortidis rhizoma. Biol Pharm Bull. 2005; 28(8): 1431-7[PubMed]
  • 5. Singh J, Kakkar P. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol. 2009; 123(1): 22-6[DOI][PubMed]
  • 6. Imanshahidi M, Hosseinzadeh H. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytother Res. 2008; 22(8): 999-1012[DOI][PubMed]
  • 7. Cheng Z, Pang T, Gu M, Gao AH, Xie CM, Li JY, et al. Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. Biochim Biophys Acta. 2006; 1760(11): 1682-9[DOI][PubMed]
  • 8. Peng WH, Wu CR, Chen CS, Chen CF, Leu ZC, Hsieh MT. Anxiolytic effect of berberine on exploratory activity of the mouse in two experimental anxiety models: interaction with drugs acting at 5-HT receptors. Life Sci. 2004; 75(20): 2451-62[DOI][PubMed]
  • 9. Fatehi M, Saleh TM, Fatehi-Hassanabad Z, Farrokhfal K, Jafarzadeh M, Davodi S. A pharmacological study on Berberis vulgaris fruit extract. J Ethnopharmacol. 2005; 102(1): 46-52[DOI][PubMed]
  • 10. Yin J, Gao Z, Liu D, Liu Z, Ye J. Berberine improves glucose metabolism through induction of glycolysis. Am J Physiol Endocrinol Metab. 2008; 294(1)-56[DOI][PubMed]
  • 11. Mikes V, Dadak V. Berberine derivatives as cationic fluorescent probes for the investigation of the energized state of mitochondria. Biochim Biophys Acta. 1983; 723(2): 231-9[PubMed]
  • 12. Mikes V, Yaguzhinskij LS. Interaction of fluorescent berberine alkyl derivatives with respiratory chain of rat liver mitochondria. J Bioenerg Biomembr. 1985; 17(1): 23-32[PubMed]
  • 13. Barreto MC, Pinto RE, Arrabaca JD, Pavao ML. Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids. Toxicol Lett. 2003; 146(1): 37-47[PubMed]
  • 14. Turner N, Li JY, Gosby A, To SW, Cheng Z, Miyoshi H, et al. Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes. 2008; 57(5): 1414-8[DOI][PubMed]
  • 15. Kong WJ, Zhang H, Song DQ, Xue R, Zhao W, Wei J, et al. Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. Metabolism. 2009; 58(1): 109-19[DOI][PubMed]
  • 16. Ni YX, Liu AQ, Gao YF, Wang WH, Song YG, Wang LH, et al. Therapeutic effect of berberine on 60 patients with non-insulin dependent diabetes mellitus and experimental research. Chin J Int Tradit West Med. 1995; 1(2): 91-5[DOI]
  • 17. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008; 57(5): 712-7[DOI][PubMed]
  • 18. Bunn HF, Haney DN, Gabbay KH, Gallop PM. Further identification of the nature and linkage of the carbohydrate in hemoglobin A1c. Biochem Biophys Res Commun. 1975; 67(1): 103-9[PubMed]
  • 19. Trivelli LA, Ranney HM, Lai HT. Hemoglobin components in patients with diabetes mellitus. N Engl J Med. 1971; 284(7): 353-7[DOI][PubMed]
  • 20. Peterson CM, Jones RL, Koenig RJ, Melvin ET, Lehrman ML. Reversible hematologic sequelae of diabetes mellitus. Ann Intern Med. 1977; 86(4): 425-9[PubMed]
  • 21. Gabbay KH, Hasty K, Breslow JL, Ellison RC, Bunn HF, Gallop PM. Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus. J Clin Endocrinol Metab. 1977; 44(5): 859-64[DOI][PubMed]
  • 22. Gonen B, Rubenstein A, Rochman H, Tanega SP, Horwitz DL. Haemoglobin A1: An indicator of the metabolic control of diabetic patients. Lancet. 1977; 2(8041): 734-7[PubMed]
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