Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

In Vitro Impact of Treatment With Aqueous Extract of Cassia Fistula on Red Blood Cell Sickling in Individuals With Sickle Cell Trait

Nazanin Heidari 1 , Foad Halvaji 2 , Parisa Rezaei Mofrad 1 , Mohammad Ali Jalali Far 3 , Mohammad Taha Jalali 2 , * and Ahmad Zare Javid 4
Authors Information
1 Student Research Committee, School of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Health Research Institute, Research Center of Thalassemia and Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
4 Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: November 01, 2015, 10 (4); e17261
  • Published Online: October 26, 2015
  • Article Type: Research Article
  • Received: April 10, 2014
  • Revised: April 7, 2015
  • Accepted: May 6, 2015
  • DOI: 10.17795/jjnpp-17261

To Cite: Heidari N, Halvaji F, Rezaei Mofrad P, Jalali Far M A, Jalali M T, et al. In Vitro Impact of Treatment With Aqueous Extract of Cassia Fistula on Red Blood Cell Sickling in Individuals With Sickle Cell Trait, Jundishapur J Nat Pharm Prod. 2015 ; 10(4):e17261. doi: 10.17795/jjnpp-17261.

Abstract
Copyright © 2015, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Footnotes
References
  • 1. McPherson RA, Pincus MR. Henry's clinical diagnosis and management by laboratory methods. 2011;
  • 2. Hoffbrand V, Moss P. Essential haematology. 2011;
  • 3. Ghosh K, Colah R, Manglani M, Choudhry VP, Verma I, Madan N, et al. Guidelines for screening, diagnosis and management of hemoglobinopathies. Indian J Hum Genet. 2014; 20(2): 101-19[DOI][PubMed]
  • 4. Steinberg MH, McCarthy WF, Castro O, Ballas SK, Armstrong FD, Smith W, et al. The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up. Am J Hematol. 2010; 85(6): 403-8[DOI][PubMed]
  • 5. Glauber JG, Wandersee NJ, Little JA, Ginder GD. 5'-flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells. Mol Cell Biol. 1991; 11(9): 4690-7[PubMed]
  • 6. De Franceschi L, Saadane N, Trudel M, Alper SL, Brugnara C, Beuzard Y. Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease. J Clin Invest. 1994; 93(4): 1670-6[DOI][PubMed]
  • 7. Brugnara C, Gee B, Armsby CC, Kurth S, Sakamoto M, Rifai N, et al. Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease. J Clin Invest. 1996; 97(5): 1227-34[DOI][PubMed]
  • 8. Brugnara C, de Franceschi L, Alper SL. Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives. J Clin Invest. 1993; 92(1): 520-6[DOI][PubMed]
  • 9. De Franceschi L, Bachir D, Galacteros F, Tchernia G, Cynober T, Alper S, et al. Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease. J Clin Invest. 1997; 100(7): 1847-52[DOI][PubMed]
  • 10. Head CA, Brugnara C, Martinez-Ruiz R, Kacmarek RM, Bridges KR, Kuter D, et al. Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo. J Clin Invest. 1997; 100(5): 1193-8[DOI][PubMed]
  • 11. Carr BI, Rahbar S, Asmeron Y, Riggs A, Winberg CD. Carcinogenicity and haemoglobin synthesis induction by cytidine analogues. Br J Cancer. 1988; 57(4): 395-402[PubMed]
  • 12. Pole S. Ayurvedic medicine: the principles of traditional practice. 2006;
  • 13. Alam MM, Siddiqui MB, Husain W. Treatment of diabetes through herbal drugs in rural India. Fitoterapia. 1990; 61(3): 240-2
  • 14. El-Saadany SS, El-Massry RA, Labib SM, Sitohy MZ. The biochemical role and hypocholesterolaemic potential of the legume Cassia fistula in hypercholesterolaemic rats. Food Nahrung. 1991; 35(8): 807-15[DOI]
  • 15. Rajan S, Baburaj DS, Sethuraman M, Parimala S. Stem and stem bark used medicinally by the Tribals Irulas and Paniyas of Nilgiri District, Tamilnadu. J Nat Remedies. 2001; 1(1): 49-54
  • 16. Siddhuraju P, Mohan P, Becker K. Studies on the antioxidant activity of Indian Laburnum (Cassia fistula L.): a preliminary assessment of crude extracts from stem bark, leaves, flowers and fruit pulp. Food Chem. 2002; 79(1): 61-7
  • 17. Barthakur NN, Arnold NP, Alli I. The Indian laburnum (Cassia fistula L.) fruit: an analysis of its chemical constituents. Plant Foods Hum Nutr. 1995; 47(1): 55-62[PubMed]
  • 18. Rauha JP, Remes S, Heinonen M, Hopia A, Kahkonen M, Kujala T, et al. Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. Int J Food Microbiol. 2000; 56(1): 3-12[PubMed]
  • 19. Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, et al. Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment. JAMA. 2003; 289(13): 1645-51[DOI][PubMed]
  • 20. McGann PT, Tshilolo L, Santos B, Tomlinson GA, Stuber S, Latham T, et al. Hydroxyurea therapy for children with sickle cell anemia in sub-Saharan Africa: Rationale and design of the REACH trial. Pediatr Blood Cancer. 2015; [DOI][PubMed]
  • 21. Ley TJ, DeSimone J, Noguchi CT, Turner PH, Schechter AN, Heller P, et al. 5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia. Blood. 1983; 62(2): 370-80[PubMed]
  • 22. Zhang C, Li X, Lian L, Chen Q, Abdulmalik O, Vassilev V, et al. Anti-sickling effect of MX-1520, a prodrug of vanillin: an in vivo study using rodents. Br J Haematol. 2004; 125(6): 788-95[DOI][PubMed]
  • 23. Gyang E, Yeom K, Hoppe C, Partap S, Jeng M. Effect of chronic red cell transfusion therapy on vasculopathies and silent infarcts in patients with sickle cell disease. Am J Hematol. 2011; 86(1): 104-6[DOI]
  • 24. Wang WC, Morales KH, Scher CD, Styles L, Olivieri N, Adams R, et al. Effect of long-term transfusion on growth in children with sickle cell anemia: results of the STOP trial. J Pediatr. 2005; 147(2): 244-7[DOI][PubMed]
  • 25. Greenway A, Ware RE, Thornburg CD. Long-term results using hydroxyurea/phlebotomy for reducing secondary stroke risk in children with sickle cell anemia and iron overload. Am J Hematol. 2011; 86(4): 357-61[DOI][PubMed]
  • 26. McLaren GD, Muir WA, Kellermeyer RW, Jacobs A. Iron Overload Disorders: Natural History, Pathogenesis, Diagnosis, and Therapy. Crit Rev Clin Lab Sci. 1983; 19(3): 205-66[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments