Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Effect of topical Nanoliposomes of Paromomycin on Rats Liver and Kidney

Heibatullah Kalantari 1 , 2 , 3 , Ali Asghar Hemmati 2 , 4 , Neda Bavarsad 5 , 6 , Annahita Rezaie 7 and Shahin Ahmadi 2 , *
Authors Information
1 Toxicology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Department of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Center Medicinal Plants Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
4 Physiology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
5 Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
6 Department of Pharmaceutics, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
7 Department of Pathobiology, Faculty of Veterinary Medicine, Shahid chamran university of Ahvaz, Ahvaz, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: November 01, 2014, 9 (4); e17565
  • Published Online: October 26, 2014
  • Article Type: Research Article
  • Received: January 14, 2014
  • Revised: March 16, 2014
  • Accepted: June 1, 2014
  • DOI: 10.17795/jjnpp-17565

To Cite: Kalantari H, Hemmati A A, Bavarsad N, Rezaie A, Ahmadi S. Effect of topical Nanoliposomes of Paromomycin on Rats Liver and Kidney, Jundishapur J Nat Pharm Prod. 2014 ; 9(4):e17565. doi: 10.17795/jjnpp-17565.

Abstract
Copyright © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Roberts LJ, Handman E, Foote SJ. Science, medicine, and the future: Leishmaniasis. BMJ. 2000; 321(7264): 801-4[PubMed]
  • 2. McConville MJ, Handman E. The molecular basis of Leishmania pathogenesis. Int J Parasitol. 2007; 37(10): 1047-51[DOI][PubMed]
  • 3. Davidson RN. Leishmaniasis. Med Trop Infect. 2005; 33(8): 43-6
  • 4. Croft SL. Monitoring drug resistance in leishmaniasis. Trop Med Int Health. 2001; 6(11): 899-905[PubMed]
  • 5. Markle WH, Makhoul K. Cutaneous leishmaniasis: recognition and treatment. Am Fam Physician. 2004; 69(6): 1455-60[PubMed]
  • 6. Topical paromomycin: a safe and effective therapy for cutaneous leishmaniasis. Dermatology progress and perspective.
  • 7. Croft SL, Yardley V. Chemotherapy of leishmaniasis. Curr Pharm Des. 2002; 8(4): 319-42[PubMed]
  • 8. Croft SL, Coombs GH. Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol. 2003; 19(11): 502-8[PubMed]
  • 9. Ferreira LS, Ramaldes GA, Nunan EA, Ferreira LA. In vitro skin permeation and retention of paromomycin from liposomes for topical treatment of the cutaneous leishmaniasis. Drug Dev Ind Pharm. 2004; 30(3): 289-96[DOI][PubMed]
  • 10. Mauel J. Macrophage-parasite interactions in Leishmania infections. J Leukoc Biol. 1990; 47(2): 187-93[PubMed]
  • 11. Ahsan F, Rivas IP, Khan MA, Torres Suarez AI. Targeting to macrophages: role of physicochemical properties of particulate carriers--liposomes and microspheres--on the phagocytosis by macrophages. J Control Release. 2002; 79(1-3): 29-40[PubMed]
  • 12. Jaafari MR, Bavarsad N, Bazzaz BS, Samiei A, Soroush D, Ghorbani S, et al. Effect of topical liposomes containing paromomycin sulfate in the course of Leishmania major infection in susceptible BALB/c mice. Antimicrob Agents Chemother. 2009; 53(6): 2259-65[DOI][PubMed]
  • 13. Forouzandeh H, Azemi ME, Rashidi I, Goudarzi M, Kalantari H. Study of the Protective Effect of Teucrium polium L. Extract on Acetaminophen-Induced Hepatotoxicity in Mice. Iran J Pharm Res. 2013; 12(1): 123-9[PubMed]
  • 14. Chatterjee P, Mukherjee A, Nandy S. Protective effects of the aqueous leaf extract of< i> Aloe barbadensis</i> on gentamicin and cisplatin–induced nephrotoxic rats. Asian Pac J Trop Biomed. 2012; 2(3)-63[DOI]
  • 15. Hottendorf GH, Williams PD. Aminoglycoside nephrotoxicity. Toxicol Pathol. 1986; 14(1): 66-72[DOI]
  • 16. Sahil K, Premjeet S, Ajay B, Middha A, Bhawna K. Stealth liposomes: a review. Int J Res Ayurveda Pharm. 2011; 2(5)
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments