Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Black Grape Seed Extract Modulates Fluoxetine-Induced Oxidative Stress and Cytotoxicity in the Mouse Testis

Zohreh Hajizadeh 1 , Malek Soleimani Mehranjani 1 , Gholamreza Najafi 2 , Seyed Mohammad Ali Shariatzadeh 1 and Ali Shalizar Jalali 2 , *
Authors Information
1 Department of Biology, Faculty of Sciences, Arak University, Arak, IR Iran
2 Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: May 01, 2016, 11 (2); e27512
  • Published Online: April 18, 2016
  • Article Type: Research Article
  • Received: February 3, 2015
  • Revised: October 29, 2015
  • Accepted: November 8, 2015
  • DOI: 10.17795/jjnpp-27512

To Cite: Hajizadeh Z, Soleimani Mehranjani M, Najafi G, Shariatzadeh S M A, Shalizar Jalali A. Black Grape Seed Extract Modulates Fluoxetine-Induced Oxidative Stress and Cytotoxicity in the Mouse Testis, Jundishapur J Nat Pharm Prod. 2016 ; 11(2):e27512. doi: 10.17795/jjnpp-27512.

Abstract
Copyright © 2016, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Pilania M, Bairwa M, Kumar N, Khanna P, Kurana H. Elderly depression in India: An emerging public health challenge. Australas Med J. 2013; 6(3): 107-11[DOI][PubMed]
  • 2. de Kerviler E, Tredaniel J, Revlon G, Groussard O, Zalcman G, Ortoli JM, et al. Fluoxetin-induced pulmonary granulomatosis. Eur Respir J. 1996; 9(3): 615-7[PubMed]
  • 3. Graudins A, Vossler C, Wang R. Fluoxetine-induced cardiotoxicity with response to bicarbonate therapy. Am J Emerg Med. 1997; 15(5): 501-3[PubMed]
  • 4. Inkielewicz-Stepniak I. Impact of fluoxetine on liver damage in rats. Pharmacol Rep. 2011; 63(2): 441-7[PubMed]
  • 5. Muller JC, Imazaki PH, Boareto AC, Lourenco EL, Golin M, Vechi MF, et al. In vivo and in vitro estrogenic activity of the antidepressant fluoxetine. Reprod Toxicol. 2012; 34(1): 80-5[DOI][PubMed]
  • 6. Bataineh HN, Daradka T. Effects of long-term use of fluoxetine on fertility parameters in adult male rats. Neuro Endocrinol Lett. 2007; 28(3): 321-5[PubMed]
  • 7. Silva J, Lins A, Amorim J, Pinto CF, Deiró TBJ, Oliveira JRM, et al. Neonatal administration of fluoxetine decreased final sertoli cell number in Wistar rats. Int. J. Morphol. 2008; 26(1): 51-62
  • 8. Agarwal A, Durairajanayagam D, du Plessis SS. Utility of antioxidants during assisted reproductive techniques: an evidence based review. Reprod Biol Endocrinol. 2014; 12: 112[DOI][PubMed]
  • 9. Hales DB, Allen JA, Shankara T, Janus P, Buck S, Diemer T, et al. Mitochondrial function in Leydig cell steroidogenesis. Ann N Y Acad Sci. 2005; 1061: 120-34[DOI][PubMed]
  • 10. Aitken RJ, Roman SD. Antioxidant systems and oxidative stress in the testes. Oxid Med Cell Longev. 2008; 1(1): 15-24[PubMed]
  • 11. Balu M, Sangeetha P, Murali G, Panneerselvam C. Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats. Brain Res Bull. 2006; 68(6): 469-73[DOI][PubMed]
  • 12. Singh RP, Tyagi AK, Dhanalakshmi S, Agarwal R, Agarwal C. Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3. Int J Cancer. 2004; 108(5): 733-40[DOI][PubMed]
  • 13. Hemmati AA, Nazari Z, Samei M. A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats. Pulm Pharmacol Ther. 2008; 21(4): 668-74[DOI][PubMed]
  • 14. Yonguc GN, Dodurga Y, Adiguzel E, Gundogdu G, Kucukatay V, Ozbal S, et al. Grape seed extract has superior beneficial effects than vitamin E on oxidative stress and apoptosis in the hippocampus of streptozotocin induced diabetic rats. Gene. 2015; 555(2): 119-26[DOI][PubMed]
  • 15. Park JS, Park MK, Oh HJ, Woo YJ, Lim MA, Lee JH, et al. Grape-seed proanthocyanidin extract as suppressors of bone destruction in inflammatory autoimmune arthritis. PLoS One. 2012; 7(12)[DOI][PubMed]
  • 16. Bayatli F, Akkus D, Kilic E, Saraymen R, Sonmez MF. The protective effects of grape seed extract on MDA, AOPP, apoptosis and eNOS expression in testicular torsion: an experimental study. World J Urol. 2013; 31(3): 615-22[DOI][PubMed]
  • 17. Zhao YM, Gao LP, Zhang HL, Guo JX, Guo PP. Grape seed proanthocyanidin extract prevents DDP-induced testicular toxicity in rats. Food Funct. 2014; 5(3): 605-11[DOI][PubMed]
  • 18. Najafi G, Nejati V, Shalizar Jalali A, Zahmatkesh E. Protective role of royal jelly in oxymetholone-induced oxidative injury in mouse testis. Iran J Toxicol. 2014; 8(25): 1073-80
  • 19. Jalali AS, Hasanzadeh S, Malekinejad H. Achillea millefolium inflorescence aqueous extract ameliorates cyclophosphamide-induced toxicity in rat testis: stereological evidences. Chin J Nat Med. 2012; 10(4): 247-54
  • 20. Shalizar Jalali A, Hasanzadeh S. Crataegus monogyna fruit aqueous extract as a protective agent against doxorubicin-induced reproductive toxicity in male rats. Avicenna J Phytomed. 2013; 3(2): 159-70[PubMed]
  • 21. Jalali AS, Hasanzadeh S, Malekinejad H. Crataegus monogyna aqueous extract ameliorates cyclophosphamide-induced toxicity in rat testis: stereological evidences. Acta Med Iran. 2012; 50(1): 1-8[PubMed]
  • 22. Gundersen HJG. Notes on the estimation of the numerical density of arbitrary profiles: the edge effect. J microsc. 1977; 111(2): 219-23
  • 23. Sakr SA, Mahran HA, El-Deeb MM. Ameliorative effect of curcumin on fluoxetine-induced reproductive toxicity and oxidative stress in male albino rats. Oxid Antioxid Med Sci. 2013; 2(1): 29-35
  • 24. Aggarwal A, Jethani SL, Rohatgi RK, Kalra J. Effects of fluoxetine on testis of albino rats–a histological assessment. Int J Sci Eng Res. 2012; 3(7): 1-5
  • 25. Simansky KJ. Serotonergic control of the organization of feeding and satiety. Behav Brain Res. 1996; 73(1-2): 37-42[PubMed]
  • 26. Morrison JL, Riggs KW, Rurak DW. Fluoxetine during pregnancy: impact on fetal development. Reprod Fertil Dev. 2005; 17(6): 641-50[PubMed]
  • 27. Katoh C, Kitajima S, Saga Y, Kanno J, Horii I, Inoue T. Assessment of quantitative dual-parameter flow cytometric analysis for the evaluation of testicular toxicity using cyclophosphamide- and ethinylestradiol-treated rats. J Toxicol Sci. 2002; 27(2): 87-96[PubMed]
  • 28. Safarinejad MR. Evaluation of endocrine profile and hypothalamic-pituitary-testis axis in selective serotonin reuptake inhibitor-induced male sexual dysfunction. J Clin Psychopharmacol. 2008; 28(4): 418-23[DOI][PubMed]
  • 29. Mruk DD, Cheng CY. Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev. 2004; 25(5): 747-806[DOI][PubMed]
  • 30. Rizk SM, Zaki HF, Mina MA. Propolis attenuates doxorubicin-induced testicular toxicity in rats. Food Chem Toxicol. 2014; 67: 176-86[DOI][PubMed]
  • 31. Kasahara E, Sato EF, Miyoshi M, Konaka R, Hiramoto K, Sasaki J, et al. Role of oxidative stress in germ cell apoptosis induced by di(2-ethylhexyl)phthalate. Biochem J. 2002; 365: 849-56[DOI][PubMed]
  • 32. Ding Y, Dai X, Jiang Y, Zhang Z, Bao L, Li Y, et al. Grape seed proanthocyanidin extracts alleviate oxidative stress and ER stress in skeletal muscle of low-dose streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats. Mol Nutr Food Res. 2013; 57(2): 365-9[DOI][PubMed]
  • 33. Roychowdhury S, Wolf G, Keilhoff G, Bagchi D, Horn T. Protection of primary glial cells by grape seed proanthocyanidin extract against nitrosative/oxidative stress. Nitric Oxide. 2001; 5(2): 137-49[DOI][PubMed]
  • 34. Puiggros F, Llopiz N, Ardevol A, Blade C, Arola L, Salvado MJ. Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems. J Agric Food Chem. 2005; 53(15): 6080-6[DOI][PubMed]
  • 35. Kabir F, Tow WW, Hamauzu Y, Katayama S, Tanaka S, Nakamura S. Antioxidant and cytoprotective activities of extracts prepared from fruit and vegetable wastes and by-products. Food Chem. 2015; 167: 358-62[DOI][PubMed]
  • 36. Ray SD, Parikh H, Hickey E, Bagchi M, Bagchi D. Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation. Mol Cell Biochem. 2001; 218(1-2): 27-33[PubMed]
  • 37. Yildirim NC, Kandemir FM, Benzer F. Beneficial effects of grape seed extract against cisplatin-induced testiculer damage in rabbits. Digest J Nanomater Biostruct. 2011; 6(1): 155-9
  • 38. Li SG, Ding YS, Niu Q, Xu SZ, Pang LJ, Ma RL, et al. Grape Seed Proanthocyanidin Extract Alleviates Arsenic-induced Oxidative Reproductive Toxicity in Male Mice. Biomed Environ Sci. 2015; 28(4): 272-80[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments