Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Preparation, Characterization and Evaluation of Antifungal Efficacy of Chitosan/Soy Phosphatidylcholine Topical Films Containing Griseofulvin

Neda Bavarsad 1 , 2 , * , Maryam Kouchak 1 , 2 , Marzieh Varmaziar 2 and Batool Sadeghi-Nejad 3
Authors Information
1 Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Department of Pharmaceutics, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Department of Mycology, School of Medicine, Abadan University of Medical Sciences, Abadan, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: May 01, 2015, 10 (2); e27562
  • Published Online: May 20, 2015
  • Article Type: Research Article
  • Received: February 1, 2015
  • Revised: March 11, 2015
  • Accepted: April 15, 2015
  • DOI: 10.17795/jjnpp-27562

To Cite: Bavarsad N, Kouchak M, Varmaziar M, Sadeghi-Nejad B. Preparation, Characterization and Evaluation of Antifungal Efficacy of Chitosan/Soy Phosphatidylcholine Topical Films Containing Griseofulvin, Jundishapur J Nat Pharm Prod. 2015 ; 10(2):e27562. doi: 10.17795/jjnpp-27562.

Copyright © 2015, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Aggarwal N, Goindi S. Preparation and evaluation of antifungal efficacy of griseofulvin loaded deformable membrane vesicles in optimized guinea pig model of Microsporum canis--dermatophytosis. Int J Pharm. 2012; 437(1-2): 277-87[DOI][PubMed]
  • 2. Ahmed SM, Ibrahim MA, Sarhan HA, Amin MA. Formulation and Characterization of Biodgradable Chitosan Films for Topical Application of Terbinafine Hcl. Bull Pharm Sci Assiut Univ. 2007; 30(2): 111
  • 3. Grant J, Blicker M, Piquette-Miller M, Allen C. Hybrid films from blends of chitosan and egg phosphatidylcholine for localized delivery of paclitaxel. J Pharm Sci. 2005; 94(7): 1512-27[DOI][PubMed]
  • 4. Esmaeili A, Beni AA. A novel fixed-bed reactor design incorporating an electrospun PVA/chitosan nanofiber membrane. J Hazard Mater. 2014; 280: 788-96[DOI][PubMed]
  • 5. Sionkowska A, Planecka A, Lewandowska K, Michalska M. The influence of UV-irradiation on thermal and mechanical properties of chitosan and silk fibroin mixtures. J Photochem Photobiol B. 2014; 140: 301-5[DOI][PubMed]
  • 6. Lai GJ, Shalumon KT, Chen SH, Chen JP. Composite chitosan/silk fibroin nanofibers for modulation of osteogenic differentiation and proliferation of human mesenchymal stem cells. Carbohydr Polym. 2014; 111: 288-97[DOI][PubMed]
  • 7. Gholipour-Kanani A, Bahrami SH, Joghataie MT, Samadikuchaksaraei A, Ahmadi-Taftie H, Rabbani S, et al. Tissue engineered poly(caprolactone)-chitosan-poly(vinyl alcohol) nanofibrous scaffolds for burn and cutting wound healing. IET Nanobiotechnol. 2014; 8(2): 123-31[DOI][PubMed]
  • 8. Azizi S, Ahmad MB, Ibrahim NA, Hussein MZ, Namvar F. Cellulose nanocrystals/ZnO as a bifunctional reinforcing nanocomposite for poly(vinyl alcohol)/chitosan blend films: fabrication, characterization and properties. Int J Mol Sci. 2014; 15(6): 11040-53[DOI][PubMed]
  • 9. Tanase CE, Spiridon I. PLA/chitosan/keratin composites for biomedical applications. Mater Sci Eng C Mater Biol Appl. 2014; 40: 242-7[DOI][PubMed]
  • 10. Kouchak M, Ameri A, Naseri B, Kargar Boldaji S. Chitosan and polyvinyl alcohol composite films containing nitrofurazone: preparation and evaluation. Iran J Basic Med Sci. 2014; 17(1): 14-20[PubMed]
  • 11. Lautenschläger H. Handbook of Cosmetic Science and Technology. 2006; : 155-63
  • 12. Vargas M, Albors A, Chiralt A, González-Martínez C. Characterization of chitosan–oleic acid composite films. Food Hydrocoll. 2009; 23(2): 536-47[DOI]
  • 13. Pereda M, Ponce AG, Marcovich NE, Ruseckaite RA, Martucci JF. Chitosan-gelatin composites and bi-layer films with potential antimicrobial activity. Food Hydrocoll. 2011; 25(5): 1372-81[DOI]
  • 14. Ojagh SM, Rezaei M, Razavi SH, Hosseini SMH. Development and evaluation of a novel biodegradable film made from chitosan and cinnamon essential oil with low affinity toward water. Food Chem. 2010; 122(1): 161-6[DOI]
  • 15. Tang C, Guan YX, Yao SJ, Zhu ZQ. Preparation of ibuprofen-loaded chitosan films for oral mucosal drug delivery using supercritical solution impregnation. Int J Pharm. 2014; 473(1-2): 434-41[DOI][PubMed]
  • 16. Rasool BK, Aziz US, Sarheed O, Rasool AA. Design and evaluation of a bioadhesive film for transdermal delivery of propranolol hydrochloride. Acta Pharm. 2011; 61(3): 271-82[DOI][PubMed]
  • 17. Jaafari MR, Bavarsad N, Bazzaz BS, Samiei A, Soroush D, Ghorbani S, et al. Effect of topical liposomes containing paromomycin sulfate in the course of Leishmania major infection in susceptible BALB/c mice. Antimicrob Agents Chemother. 2009; 53(6): 2259-65[DOI][PubMed]
  • 18. Martin's Physical Pharmacy and Pharmaceutical Sciences. 2006; : 228-48
  • 19. Gajra B, Pandya SS, Singh S, Rabari HA. Mucoadhesive hydrogel films of econazole nitrate: formulation and optimization using factorial design. J Drug Deliv. 2014; 2014: 305863[DOI][PubMed]
  • 20. Aggarwal N, Goindi S, Mehta SD. Preparation and evaluation of dermal delivery system of griseofulvin containing vitamin E-TPGS as penetration enhancer. AAPS PharmSciTech. 2012; 13(1): 67-74[DOI][PubMed]
  • 21. Kassem MA, Esmat S, Bendas ER, El-Komy MH. Efficacy of topical griseofulvin in treatment of tinea corporis. Mycoses. 2006; 49(3): 232-5[DOI][PubMed]
  • 22. Kołodziejska I, Kaczorowski K, Piotrowska B, Sadowska M. Modification of the properties of gelatin from skins of Baltic cod (Gadus morhua) with transglutaminase. Food Chem. 2004; 86(2): 203-9[DOI]
  • 23. Senel S, Ikinci G, Kas S, Yousefi-Rad A, Sargon MF, Hincal AA. Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery. Int J Pharm. 2000; 193(2): 197-203[PubMed]
  • 24. Jridi M, Hajji S, Ayed HB, Lassoued I, Mbarek A, Kammoun M, et al. Physical, structural, antioxidant and antimicrobial properties of gelatin-chitosan composite edible films. Int J Biol Macromol. 2014; 67: 373-9[DOI][PubMed]
  • 25. Caner C, Vergano PJ, Wiles JL. Chitosan Film Mechanical and Permeation Properties as Affected by Acid, Plasticizer, and Storage. J Food Sci. 2006; 63(6): 1049-53[DOI]
  • 26. Costa Idos S, Abranches RP, Garcia MT, Pierre MB. Chitosan-based mucoadhesive films containing 5-aminolevulinic acid for buccal cancer's treatment. J Photochem Photobiol B. 2014; 140: 266-75[DOI][PubMed]
  • 27. Queen D, Evans JH, Gaylor JDS, Courtney JM, Reid WH. An in vitro assessment of wound dressing conformability. Biomater . 1987; 8(5): 372-6[DOI]
  • 28. Binsi PK, Ravishankar CN, Srinivasa Gopal TK. Development and characterization of an edible composite film based on chitosan and virgin coconut oil with improved moisture sorption properties. J Food Sci. 2013; 78(4)-34[DOI][PubMed]
  • 29. Hermans K, Van den Plas D, Kerimova S, Carleer R, Adriaensens P, Weyenberg W, et al. Development and characterization of mucoadhesive chitosan films for ophthalmic delivery of cyclosporine A. Int J Pharm. 2014; 472(1-2): 10-9[DOI][PubMed]
  • 30. Budai L, Kaszas N, Grof P, Lenti K, Maghami K, Antal I, et al. Liposomes for topical use: a physico-chemical comparison of vesicles prepared from egg or soy lecithin. Sci Pharm. 2013; 81(4): 1151-66[DOI][PubMed]
  • 31. Chhonker YS, Prasad YD, Chandasana H, Vishvkarma A, Mitra K, Shukla PK, et al. Amphotericin-B entrapped lecithin/chitosan nanoparticles for prolonged ocular application. Int J Biol Macromol. 2015; 72: 1451-8[DOI][PubMed]
  • 32. Sajomsang W, Gonil P, Saesoo S, Ovatlarnporn C. Antifungal property of quaternized chitosan and its derivatives. Int J Biol Macromol. 2012; 50(1): 263-9[DOI][PubMed]
  • 33. Dantas MD, Cavalcante DR, Araujo FE, Barretto SR, Aciole GT, Pinheiro AL, et al. Improvement of dermal burn healing by combining sodium alginate/chitosan-based films and low level laser therapy. J Photochem Photobiol B. 2011; 105(1): 51-9[DOI][PubMed]
  • 34. Abruzzo A, Bigucci F, Cerchiara T, Cruciani F, Vitali B, Luppi B. Mucoadhesive chitosan/gelatin films for buccal delivery of propranolol hydrochloride. Carbohydr Polym. 2012; 87(1): 581-8[DOI]
  • 35. Stefanescu C, Daly WH, Negulescu II. Biocomposite films prepared from ionic liquid solutions of chitosan and cellulose. Carbohydr Polym. 2012; 87(1): 435-43[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments