Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Gold Nanoparticle and Mean Inactivation Dose of Human Intestinal Colon Cancer HT-29 Cells

Zahra Arab-Bafrani 1 , 2 , Alihossein Saberi 3 , * , Mohammad Javad Tahmasebi Birgani 2 , Daryoush Shahbazi-Gahrouei 4 , Mahdi Abbasian 5 and Mehrafarin Fesharaki 6
Authors Information
1 Disorder Metabolic Research Center, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, IR Iran
2 Department of Medical Physics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Department of Medical Genetics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
4 Department of Medical Physics and Medical Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR Iran
5 Department of Biotechnology, College of Agriculture, Isfahan University of Technology, Isfahan, IR Iran
6 Department of Cell Sciences Research Center Medical Science, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: December 01, 2015, 10 (4); e29153
  • Published Online: December 21, 2015
  • Article Type: Research Article
  • Received: May 16, 2015
  • Revised: July 11, 2015
  • Accepted: July 17, 2015
  • DOI: 10.17795/jjnpp-29153

To Cite: Arab-Bafrani Z, Saberi A, Tahmasebi Birgani M J, Shahbazi-Gahrouei D, Abbasian M, et al. Gold Nanoparticle and Mean Inactivation Dose of Human Intestinal Colon Cancer HT-29 Cells, Jundishapur J Nat Pharm Prod. 2015 ; 10(4):e29153. doi: 10.17795/jjnpp-29153.

Copyright © 2015, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Azadeh S, Moghimi-Dehkordi B, Fatem SR, Pourhoseingholi MA, Ghiasi S, Zali MR. Colorectal cancer in Iran: an epidemiological study. Asia Pac J Cancer Prevent. 2007; 9(1): 123-6
  • 2. Albuquerque C. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Human Mol Gene. 2002; 11(13): 1549-60[DOI]
  • 3. Chen WS, Lee YJ, Yu YC, Hsaio CH, Yen JH, Yu SH, et al. Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin. Int J Radiat Oncol Biol Phys. 2010; 77(5): 1527-35[DOI][PubMed]
  • 4. Xu Y. Induction of genetic instability by gain-of-function p53 cancer mutants. Oncogene. 2008; 27(25): 3501-7[DOI][PubMed]
  • 5. Andreyev HJ. Gastrointestinal problems after pelvic radiotherapy: the past, the present and the future. Clin Oncol (R Coll Radiol). 2007; 19(10): 790-9[DOI][PubMed]
  • 6. Jain S, Hirst DG, O'Sullivan JM. Gold nanoparticles as novel agents for cancer therapy. Br J Radiol. 2012; 85(1010): 101-13[DOI][PubMed]
  • 7. Smith L, Kuncic Z, Ostrikov K, Kumar S. Nanoparticles in Cancer Imaging and Therapy. J Nanomater. 2012; 2012: 1-7[DOI]
  • 8. Jiang W, Kim BY, Rutka JT, Chan WC. Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnol. 2008; 3(3): 145-50[DOI][PubMed]
  • 9. Nativo P, Prior IA, Brust M. Uptake and intracellular fate of surface-modified gold nanoparticles. ACS Nano. 2008; 2(8): 1639-44[DOI][PubMed]
  • 10. Jain S, Coulter JA, Hounsell AR, Butterworth KT, McMahon SJ, Hyland WB, et al. Cell-specific radiosensitization by gold nanoparticles at megavoltage radiation energies. Int J Radiat Oncol Biol Phys. 2011; 79(2): 531-9[DOI][PubMed]
  • 11. McMahon SJ, Hyland WB, Muir MF, Coulter JA, Jain S, Butterworth KT, et al. Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles. Sci Rep. 2011; 1: 18[DOI][PubMed]
  • 12. Rahman WN, Bishara N, Ackerly T, He CF, Jackson P, Wong C, et al. Enhancement of radiation effects by gold nanoparticles for superficial radiation therapy. Nanomed Nanotechnol Biol Med. 2009; 5(2): 136-42[DOI]
  • 13. Xiao F, Zheng Y, Cloutier P, He Y, Hunting D, Sanche L. On the role of low-energy electrons in the radiosensitization of DNA by gold nanoparticles. Nanotechnology. 2011; 22(46): 465101[DOI][PubMed]
  • 14. Fertil B, Dertinger H, Courdi A, Malaise EP. Mean inactivation dose: a useful concept for intercomparison of human cell survival curves. Radiat Res. 1984; 99(1): 73-84[PubMed]
  • 15. Belli M, Simula S. The calculation of the mean inactivation dose by approximated methods. Radiat Res. 1991; 128(1): 112-4[PubMed]
  • 16. Price P, McMillan TJ. Use of the tetrazolium assay in measuring the response of human tumor cells to ionizing radiation. Cancer Res. 1990; 50(5): 1392-6
  • 17. Buch K, Peters T, Nawroth T, Sanger M, Schmidberger H, Langguth P. Determination of cell survival after irradiation via clonogenic assay versus multiple MTT Assay--a comparative study. Radiat Oncol. 2012; 7: 1[DOI][PubMed]
  • 18. Brenner DJ. The linear-quadratic model is an appropriate methodology for determining isoeffective doses at large doses per fraction. Semin Radiat Oncol. 2008; 18(4): 234-9[DOI][PubMed]
  • 19. Weichselbaum RR, Beckett MA, Vijayakumar S, Simon MA, Awan AM, Nachman J, et al. Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy. Int J Radiat Oncol Biol Phys. 1990; 19(2): 313-9[DOI]
  • 20. Cho SH. Estimation of tumour dose enhancement due to gold nanoparticles during typical radiation treatments: a preliminary Monte Carlo study. Phys Med Biol. 2005; 50(15)-73[DOI][PubMed]
  • 21. Roa W, Zhang X, Guo L, Shaw A, Hu X, Xiong Y, et al. Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle. Nanotechnology. 2009; 20(37): 375101[DOI][PubMed]
  • 22. Kong T, Zeng J, Wang X, Yang X, Yang J, McQuarrie S, et al. Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticles. Small. 2008; 4(9): 1537-43[DOI][PubMed]
  • 23. Patra HK, Banerjee S, Chaudhuri U, Lahiri P, Dasgupta AK. Cell selective response to gold nanoparticles. Nanomedicine. 2007; 3(2): 111-9[DOI][PubMed]
  • 24. Wang C, Li X, Wang Y, Liu Z, Fu L, Hu L. Enhancement of radiation effect and increase of apoptosis in lung cancer cells by thio-glucose-bound gold nanoparticles at megavoltage radiation energies. J Nanopart Res. 2013; 15(5): 1-12[DOI]
  • 25. McMahon SJ, Hyland WB, Muir MF, Coulter JA, Jain S, Butterworth KT, et al. Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy. Radiother Oncol. 2011; 100(3): 412-6[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments