Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Formulation Development of a Topical Probiotic Gel for Antidermatophytosis Effect

Sannaz Mehdi-Alamdarloo 1 , Abdolghani Ameri 2 , Eskandar Moghimipour 1 , 3 , Sahar Gholipour 2 and Afrooz Saadatzadeh 2 , 3 , *
Authors Information
1 Department of Pharmaceutics, Faculty of Pharmacy, Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Department of Food and Drug Control, Faculty of Pharmacy, Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: August 01, 2016, 11 (3); e35893
  • Published Online: March 15, 2016
  • Article Type: Research Article
  • Received: January 6, 2016
  • Revised: February 7, 2016
  • Accepted: February 17, 2016
  • DOI: 10.17795/jjnpp-35893

To Cite: Mehdi-Alamdarloo S, Ameri A, Moghimipour E, Gholipour S, Saadatzadeh A. Formulation Development of a Topical Probiotic Gel for Antidermatophytosis Effect, Jundishapur J Nat Pharm Prod. 2016 ; 11(3):e35893. doi: 10.17795/jjnpp-35893.

Copyright © 2016, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Esquenazi D, Alviano CS, de Souza W, Rozental S. The influence of surface carbohydrates during in vitro infection of mammalian cells by the dermatophyte Trichophyton rubrum. Res Microbiol. 2004; 155(3): 144-53[DOI][PubMed]
  • 2. Frey D, Oldfield RJ, Bridger RC. A colour atlas of pathogenic fungi. 1979;
  • 3. Seebacher C, Bouchara JP, Mignon B. Updates on the epidemiology of dermatophyte infections. Mycopathologia. 2008; 166(5-6): 335-52[DOI][PubMed]
  • 4. Havlickova B, Czaika VA, Friedrich M. Epidemiological trends in skin mycoses worldwide. Mycoses. 2008; 51 Suppl 4: 2-15[DOI][PubMed]
  • 5. Coelho LM, Aquino-Ferreira R, Maffei CM, Martinez-Rossi NM. In vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia. J Antimicrob Chemother. 2008; 62(4): 758-61[DOI][PubMed]
  • 6. Peres NT, Maranhao FC, Rossi A, Martinez-Rossi NM. Dermatophytes: host-pathogen interaction and antifungal resistance. An Bras Dermatol. 2010; 85(5): 657-67[PubMed]
  • 7. Back DJ, Tjia JF. Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes. Br J Clin Pharmacol. 1991; 32(5): 624-6[PubMed]
  • 8. Baginski M, Czub J. Amphotericin B and its new derivatives - mode of action. Curr Drug Metab. 2009; 10(5): 459-69[PubMed]
  • 9. Lilly DM, Stillwell RH. Probiotics: Growth-Promoting Factors Produced by Microorganisms. Science. 1965; 147(3659): 747-8[PubMed]
  • 10. Harish K, Varghese T. Probiotics in human-evidence based review. Calicut Med J. 2006; 4: 3
  • 11. Vinderola G, Matar C, Palacios J, Perdigon G. Mucosal immunomodulation by the non-bacterial fraction of milk fermented by Lactobacillus helveticus R389. Int J Food Microbiol. 2007; 115(2): 180-6[DOI][PubMed]
  • 12. Sit CS, Vederas JC. Approaches to the discovery of new antibacterial agents based on bacteriocins. Biochem Cell Biol. 2008; 86(2): 116-23[DOI][PubMed]
  • 13. Foo HL, Loh TC, Lai PW, Lim YZ, Kufli CN, Rusul G. Effects of Adding Lactobacillus plantarum I-UL4 Metabolites in Drinking Water of Rats. Pak J Nutr. 2003; 2(5): 283-8[DOI]
  • 14. Lavermicocca P, Valerio F, Visconti A. Antifungal activity of phenyllactic acid against molds isolated from bakery products. Appl Environ Microbiol. 2003; 69(1): 634-40[PubMed]
  • 15. Ryan LA, Dal Bello F, Arendt EK. The use of sourdough fermented by antifungal LAB to reduce the amount of calcium propionate in bread. Int J Food Microbiol. 2008; 125(3): 274-8[DOI][PubMed]
  • 16. Bhowmik D. Recent advances in novel topical drug delivery system. Pharm Innov. 2012; 1(9)
  • 17. Basha BN, Prakasam K, Goli D. Formulation and evaluation of gel containing fluconazole-antifungal agent. Int J Drug Dev Res. 2011;
  • 18. Chandak AR, Verma PRP. Development and Evaluation of HPMC Based Matrices for Transdermal Patches of Tramadol. Clin Res Regulat Affairs. 2008; 25(1): 13-30[DOI]
  • 19. Fu XC, Wang GP, Liang WQ, Chow MS. Prediction of drug release from HPMC matrices: effect of physicochemical properties of drug and polymer concentration. J Control Release. 2004; 95(2): 209-16[DOI][PubMed]
  • 20. Saadatzadeh A, Fazeli MR, Jamalifar H, Dinarvand R. Probiotic Properties of Lyophilized Cell Free Extract of Lactobacillus casei. Jundishapur J Nat Pharm Prod. 2013; 8(3): 131-7[PubMed]
  • 21. Ghaffari S, Varshosaz J, Saadat A, Atyabi F. Stability and antimicrobial effect of amikacin-loaded solid lipid nanoparticles. Int J Nanomedicine. 2011; 6: 35-43[DOI][PubMed]
  • 22. Garg A, Gupta V, Gaikwad S, Deol P, Mishra NK, Sharma MC, et al. Spinal angiolipoma: report of three cases and review of MRI features. Australas Radiol. 2002; 46(1): 84-90[PubMed]
  • 23. Ruiz Martinez MA, Lopez-Viota Gallardo J, de Benavides MM, de Dios Garcia Lopez-Duran J, Gallardo Lara V. Rheological behavior of gels and meloxicam release. Int J Pharm. 2007; 333(1-2): 17-23[DOI][PubMed]
  • 24. Moghimipour E, Ameri A, Saudatzadeh A, Salimi A. Formulation of an anti-dermatophyte cream from hydro-alcoholic extract of eucalyptus camaldulensis leaves. Jundishapur J Nat Pharm Prod. 2009; 4(1): 32-40
  • 25. Karska-Wysocki B, Bazo M, Smoragiewicz W. Antibacterial activity of Lactobacillus acidophilus and Lactobacillus casei against methicillin-resistant Staphylococcus aureus (MRSA). Microbiol Res. 2010; 165(8): 674-86[DOI][PubMed]
  • 26. Guo J, Brosnan B, Furey A, Arendt E, Murphy P, Coffey A. Antifungal activity of Lactobacillus against Microsporum canis, Microsporum gypseum and Epidermophyton floccosum. Bioeng Bugs. 2012; 3(2): 104-13[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments