Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Phytochemical Evaluation and Antioxidant Activity of Essential Oil, and Aqueous and Organic Extracts of Artemisia dracunculus

Arezoo Rajabian 1 , Mohamad Hassanzadeh Khayyat 2 , Seyed Ahmad Emami 3 , Zahra Tayarani-Najaran 4 , Reza Rahimzadeh Oskooie 5 and Javad Asili 3 , *
Authors Information
1 Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2 Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
4 Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
5 Students Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: February 2017, 12 (1); e32325
  • Published Online: November 8, 2016
  • Article Type: Research Article
  • Received: October 8, 2015
  • Revised: October 7, 2016
  • Accepted: October 16, 2016
  • DOI: 10.5812/jjnpp.32325

To Cite: Rajabian A, Hassanzadeh Khayyat M, Emami S A, Tayarani-Najaran Z, Rahimzadeh Oskooie R, et al. Phytochemical Evaluation and Antioxidant Activity of Essential Oil, and Aqueous and Organic Extracts of Artemisia dracunculus, Jundishapur J Nat Pharm Prod. 2017 ; 12(1):e32325. doi: 10.5812/jjnpp.32325.

Copyright © 2016, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Zhao G, Xiang Z, Ye T, Yuan Y, Guo Z. Antioxidant activities of Salvia miltiorrhiza and Panax notoginseng. Food Chem. 2006; 99(4): 767-74[DOI]
  • 2. Kordali S, Kotan R, Mavi A, Cakir A, Ala A, Yildirim A. Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils. J Agric Food Chem. 2005; 53(24): 9452-8[DOI][PubMed]
  • 3. Kulisic T, Radonic A, Katalinic V, Milos M. Use of different methods for testing antioxidative activity of oregano essential oil. Food Chem. 2004; 85(4): 633-40[DOI]
  • 4. Ruberto G, Baratta MT. Antioxidant activity of selected essential oil components in two lipid model systems. Food Chem. 2000; 69(2): 167-74[DOI]
  • 5. Milos M. Chemical composition and antioxidant effect of glycosidically bound volatile compounds from oregano (Origanum vulgare L. ssp. hirtum). Food Chem. 2000; 71(1): 79-83[DOI]
  • 6. Abad MJ, Bedoya LM, Apaza L, Bermejo P. The Artemisia L. Genus: a review of bioactive essential oils. Molecules. 2012; 17(3): 2542-66[DOI][PubMed]
  • 7. Ghahreman A, Attar F. Biodiversity of plant species in iran. Tehran university publication. Tehran. 1999;
  • 8. Emami SA, Aghazari F. Les Phanerogames endemiques de la flore d'Iran de l'. 2007; : 349
  • 9. Tan RX, Tang HQ, Hu J, Shuai B. Lignans and sesquiterpene lactones from Artemisia sieversiana and Inula racemosa. Phytochemistry. 1998; 49(1): 157-61[PubMed]
  • 10. Bora KS, Sharma A. The genus Artemisia: a comprehensive review. Pharm Biol. 2011; 49(1): 101-9[DOI][PubMed]
  • 11. Efferth T. Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside. Planta Med. 2007; 73(4): 299-309[DOI][PubMed]
  • 12. Zheng GQ. Cytotoxic terpenoids and flavonoids from Artemisia annua. Planta Med. 1994; 60(1): 54-7[DOI][PubMed]
  • 13. Kordali S, Cakir A, Mavi A, Kilic H, Yildirim A. Screening of chemical composition and antifungal and antioxidant activities of the essential oils from three Turkish Artemisia species. J Agric Food Chem. 2005; 53(5): 1408-16[DOI][PubMed]
  • 14. Repetto MG, Llesuy SF. Antioxidant properties of natural compounds used in popular medicine for gastric ulcers. Braz J Med Biol Res. 2002; 35(5): 523-34[PubMed]
  • 15. Canadanovic-Brunet JM, Djilas SM, Cetkovic GS, Tumbas VT. Free-radical scavenging activity of wormwood (Artemisia absinthium L.) extracts. J Sci Food Agr. 2005; 85(2): 265-72[DOI]
  • 16. Liu CZ, Murch SJ, El-Demerdash M, Saxena PK. Artemisia judaica L.: micropropagation and antioxidant activity. J Biotechnol. 2004; 110(1): 63-71[DOI][PubMed]
  • 17. Mohammadi A, Sani TA, Ameri AA, Imani M, Golmakani E, Kamali H. Seasonal variation in the chemical composition, antioxidant activity, and total phenolic content of Artemisia absinthium essential oils. Pharmacognosy Res. 2014; 7(4): 329-34[DOI][PubMed]
  • 18. Maria AO, Repetto M, Llesuy S, Giordano O, Guzman J, Guerreiro E. Antioxidant activity of Artemisia douglasiana besser extract and dehydroleucodine. Phytother Res. 2000; 14(7): 558-60[PubMed]
  • 19. Bahramikia S, Yazdanparast R, Nosrati N. A comparision of antioxidant capacities of ethanol extracts of satureja hortensis and artemisiadracunculus leaves. Pharmacologyonline. 2008; 2: 694-704
  • 20. Kemal D, Elvira KB, Haris N, Emin S. Antioxidant activity of water extracts and essential oil of Artemisia Dracunculus L. Asteraceae. Medical Journal. 2013; 19(2): 94-9
  • 21. Chaleshtori RS, Rokni N, Razavilar V, Kopaei MR. The evaluation of the antibacterial and antioxidant activity of Tarragon (Artemisia dracunculus L.) essential oil and its chemical composition. Jundishapur J Microbiol. 2013; 6(9)
  • 22. Teixeira B, Marques A, Ramos C, Neng NR, Nogueira JMF, Saraiva JA, et al. Chemical composition and antibacterial and antioxidant properties of commercial essential oils. Ind Crops Prod. 2013; 43: 587-95[DOI]
  • 23. Adams RP, Zanoni TA, Hogge L. The volatile leaf oils of Juniperus flaccida var. flaccida and var. poblana. J Nat Prod. 1984; 47(6): 1064-5[DOI]
  • 24. Rojas G, Levaro J, Tortoriello J, Navarro V. Antimicrobial evaluation of certain plants used in Mexican traditional medicine for the treatment of respiratory diseases. J Ethnopharmacol. 2001; 74(1): 97-101[PubMed]
  • 25. Saha K, Lajis NH, Israf DA, Hamzah AS, Khozirah S, Khamis S, et al. Evaluation of antioxidant and nitric oxide inhibitory activities of selected Malaysian medicinal plants. J Ethnopharmacol. 2004; 92(2-3): 263-7[DOI][PubMed]
  • 26. Tayarani-Najaran Z, Emami SA, Asili J, Mirzaei A, Mousavi SH. Analyzing cytotoxic and apoptogenic properties of Scutellaria litwinowii root extract on cancer cell lines. Evid Based Complement Alternat Med. 2011; 2011
  • 27. Adams RP. Identification of essential oil components by gas chromatography/mass spectroscopy. J Am Soc Mass Spectrom. 1997; 6(8): 671-2
  • 28. Singh R, Singh S, Kumar S, Arora S. Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn. Food Chem Toxicol. 2007; 45(7): 1216-23[DOI][PubMed]
  • 29. Adedapo AA, Jimoh FO, Afolayan AJ, Masika PJ. Antioxidant activities and phenolic contents of the methanol extracts of the stems of Acokanthera oppositifolia and Adenia gummifera. BMC Complement Altern Med. 2008; 8: 54[DOI][PubMed]
  • 30. Al-Fatimi M, Wurster M, Schroder G, Lindequist U. Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen. J Ethnopharmacol. 2007; 111(3): 657-66[DOI][PubMed]
  • 31. Ayoola GA, Ipav SS, Sofidiya MO, Adepoju-Bello AA, Coker HAB, Odugbemi TO. Phytochemical screening and free radical scavenging activities of the fruits and leaves of Allanblackia floribunda Oliv (Guttiferae). Int J Health Res. 2008; 1(2): 87-93
  • 32. Kirby AJ, Schmidt RJ. The antioxidant activity of Chinese herbs for eczema and of placebo herbs--I. J Ethnopharmacol. 1997; 56(2): 103-8[PubMed]
  • 33. Neergheen VS, Soobrattee MA, Bahorun T, Aruoma OI. Characterization of the phenolic constituents in Mauritian endemic plants as determinants of their antioxidant activities in vitro. J Plant Physiol. 2006; 163(8): 787-99[DOI][PubMed]
  • 34. The NIST Chemistry WebBook.
  • 35. Ayoughi F, Barzegar M, Sahari MA, Naghdibadi H. Chemical compositions of essential oils of Artemisia dracunculus L. and endemic Matricaria chamomilla L. and an evaluation of their antioxidative effects. J Agr Sci Tech. 2010; 13: 79-88
  • 36. Karagozler AA, Erdag B, Emek YC, Uygun DA. Antioxidant activity and proline content of leaf extracts from Dorystoechas hastata. Food Chem. 2008; 111(2): 400-7[DOI][PubMed]
  • 37. Lopes-Lutz D, Alviano DS, Alviano CS, Kolodziejczyk PP. Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry. 2008; 69(8): 1732-8[DOI][PubMed]
  • 38. Kumar KS, Ganesan K, Rao PVS. Antioxidant potential of solvent extracts of Kappaphycus alvarezii (Doty) Doty–An edible seaweed. Food chem. 2008; 107(1): 289-95
  • 39. Tachakittirungrod S, Okonogi S, Chowwanapoonpohn S. Study on antioxidant activity of certain plants in Thailand: Mechanism of antioxidant action of guava leaf extract. Food Chem. 2007; 103(2): 381-8
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments