Jundishapur Journal of Natural Pharmaceutical Products

Published by: Kowsar

Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying

Oluwaseun Ruth Alara 1 , * , Nour Hamid Abdurahman 1 , Siti Kholijah Abdul Mudalip 1 and Olusegun Abayomi Olalere 1
Authors Information
1 Faculty of Chemical and Natural Resources Engineering, Universiti Malaysia Pahang, Gambang, Pahang, Malaysia
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: 14 (1); e57620
  • Published Online: December 9, 2018
  • Article Type: Research Article
  • Received: July 5, 2017
  • Revised: November 28, 2017
  • Accepted: February 17, 2018
  • DOI: 10.5812/jjnpp.57620

To Cite: Alara O R, Abdurahman N H, Abdul Mudalip S K, Olalere O A. Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying, Jundishapur J Nat Pharm Prod. Online ahead of Print ; 14(1):e57620. doi: 10.5812/jjnpp.57620.

Abstract
Copyright © 2018, Jundishapur Journal of Natural Pharmaceutical Products. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results and Discussion
5. Conclusions
Footnotes
References
  • 1. Toyang NJ, Verpoorte R. A review of the medicinal potentials of plants of the genus Vernonia (Asteraceae). J Ethnopharmacol. 2013;146(3):681-723. doi: 10.1016/j.jep.2013.01.040. [PubMed: 23395623].
  • 2. Alara OR, Abdurahman NH, Abdul Mudalip SK, Olalere OA. Phytochemical and pharmacological properties of Vernonia amygdalina: A review. J Chem Eng Ind Biotechnol. 2017;80:96. doi: 10.15282/JCEIB-V2-07.29/9/2017/2.2.
  • 3. Kadiri O, Olawoye B. Vernonia amygdalina: An underutilized vegetable with nutraceutical potentials: A review. Turkish J Agric Food Sci Technol. 2016;4(9):763-8. doi: 10.24925/turjaf.v4i9.763-768.570.
  • 4. Alara OR, Abdurahman NH, Abdul Mudalip SK, Olalere OA. Effect of drying methods on the free radicals scavenging activity of Vernonia amygdalina growing in Malaysia. J King Saud Univ Sci. 2017. doi: 10.1016/j.jksus.2017.05.018.
  • 5. Sha'a KK, Oguche S, Watila IM, Ikpa TF. In vitro aantimalarial activity of the extracts of Vernonia amygdalina commonly used in traditional medicine in Nigeria. Sci World J. 2011;6(2):5-9.
  • 6. Yeap SK, Ho WY, Beh BK, San Liang W, Ky H, Yousr AHN, et al. Vernonia amygdalina, an ethnoveterinary and ethnomedical used green vegetable with multiple bio-activities. J Med Plant Res. 2010;4(25):2787-812.
  • 7. Atangwho IJ, Egbung GE, Ahmad M, Yam MF, Asmawi MZ. Antioxidant versus anti-diabetic properties of leaves from Vernonia amygdalina Del. growing in Malaysia. Food Chem. 2013;141(4):3428-34. doi: 10.1016/j.foodchem.2013.06.047. [PubMed: 23993503].
  • 8. Erasto P, Grierson DS, Afolayan AJ. Evaluation of antioxidant activity and the fatty acid profile of the leaves of Vernonia amygdalina growing in South Africa. Food chem. 2007;104(2):636-42. doi: 10.1016/j.foodchem.2006.12.013.
  • 9. Alara OR, Abdurahman NH, Olalere OA. Optimization of microwave-assisted extraction of flavonoids and antioxidants from Vernonia amygdalina leaf using response surface methodology. Food Bioprod Process. 2018;107:36-8. doi: 10.1016/j.fbp.2017.10.007.
  • 10. Kiplimo JJ, Koorbanally NA, Chenia H. Triterpenoids from Vernonia auriculifera Hiern exhibit antimicrobial activity. African J Pharm Pharmacol. 2011;5(8):1150-6. doi: 10.5897/AJPP11.183.
  • 11. Farombi EO, Owoeye O. Antioxidative and chemopreventive properties of Vernonia amygdalina and Garcinia biflavonoid. Int J Environ Res Public Health. 2011;8(6):2533-55. doi: 10.3390/ijerph8062533. [PubMed: 21776245]. [PubMed Central: PMC3138040].
  • 12. Alara OR, Abdurahman NH, Olalere OA. Ethanolic extraction of flavonoids, phenolics and antioxidants from Vernonia amygdalina leaf using two-level factorial design. J King Saud Univ Sci. 2017. doi: 10.1016/j.jksus.2017.08.001.
  • 13. Wong FC, Woo CC, Hsu A, Tan BK. The anti-cancer activities of Vernonia amygdalina extract in human breast cancer cell lines are mediated through caspase-dependent and p53-independent pathways. PLoS One. 2013;8(10). e78021. doi: 10.1371/journal.pone.0078021. [PubMed: 24205071]. [PubMed Central: PMC3812032].
  • 14. Azwanida NN. A review on the extraction methods use in medicinal plants, principle, strength and limitation. Med Aromat Plants. 2015;4(3):3-8. doi: 10.4172/2167-0412.1000196.
  • 15. Chan CH, Yusoff R, Ngoh GC, Kung FW. Microwave-assisted extractions of active ingredients from plants. J Chromatogr A. 2011;1218(37):6213-25. doi: 10.1016/j.chroma.2011.07.040. [PubMed: 21820119].
  • 16. Adámková A, Kouřimská L, Kadlecová B. The effect of drying on antioxidant activity of selected Lamiaceae herbs. Potravinarstvo Slovak J Food Sci. 2015;9(1):252-7. doi: 10.5219/474.
  • 17. Vyankatrao NP, Arts NTA, Commerce VSRS. Effect of drying methods on nutritional value of some vegetables. Proceeding of the National Conference on Conservation of Natural Resources & Biodiversity for Sustainable Development. Biosci. Discov. 2014. p. 72-9.
  • 18. Saravanan S, Parimelazhagan T. In vitro antioxidant, antimicrobial and anti-diabetic properties of polyphenols of Passiflora ligularis Juss. fruit pulp. Food Sci Hum Wellness. 2014;3(2):56-64. doi: 10.1016/j.fshw.2014.05.001.
  • 19. Dahmoune F, Spigno G, Moussi K, Remini H, Cherbal A, Madani K. Pistacia lentiscus leaves as a source of phenolic compounds: Microwave-assisted extraction optimized and compared with ultrasound-assisted and conventional solvent extraction. Ind Crops Prod. 2014;61:31-40. doi: 10.1016/j.indcrop.2014.06.035.
  • 20. Ayoola GA, Coker HA, Adesegun SA, Adepoju-Bello AA, Obaweya K, Ezennia EC, et al. Phytochemical screening and antioxidant activities of some selected medicinal plants used for malaria therapy in Southwestern Nigeria. Trop J Pharm Res. 2008;7(3):1019-24. doi: 10.4314/tjpr.v7i3.14686.
  • 21. Alam MN, Bristi NJ, Rafiquzzaman M. Review on in vivo and in vitro methods evaluation of antioxidant activity. Saudi Pharm J. 2013;21(2):143-52. doi: 10.1016/j.jsps.2012.05.002. [PubMed: 24936134]. [PubMed Central: PMC4052538].
  • 22. Thaipong K, Boonprakob U, Crosby K, Cisneros-Zevallos L, Byrne DH. Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts. J Food Compos Anal. 2006;19(6-7):669-75. doi: 10.1016/j.jfca.2006.01.003.
  • 23. Pan X, Niu G, Liu H. Microwave-assisted extraction of tea polyphenols and tea caffeine from green tea leaves. Chem Eng Process. 2003;42(2):129-33. doi: 10.1016/S0255-2701(02)00037-5.
  • 24. Hithamani G, Ramalakshmi K. Microwave assisted extraction of phenolics from Origanum vulgare. Int Invent J Agric Soil Sci. 2013;1(1):7-12.
  • 25. Okoduwa SI, Umar IA, James DB, Inuwa HM, Habila JD. Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants. World J Diabetes. 2016;7(20):605-14. doi: 10.4239/wjd.v7.i20.605. [PubMed: 28031778]. [PubMed Central: PMC5155234].
  • 26. Spigno G, De Faveri DM. Microwave-assisted extraction of tea phenols: A phenomenological study. J Food Eng. 2009;93(2):210-7. doi: 10.1016/j.jfoodeng.2009.01.006.
  • 27. Veggi PC, Martinez J, Meireles MA. Microwave-assisted extraction for bioactive compounds. Boston, MA: Springer; 2013.
  • 28. Desai M, Parikh J, Parikh PA. Extraction of natural products using microwaves as a heat source. Sep Purif Rev. 2010;39(1-2):1-32. doi: 10.1080/15422111003662320.
  • 29. Chew KK, Khoo MZ, Ng SY, Thoo YY, Aida WWM, Ho CW. Effect of ethanol concentration, extraction time and extraction temperature on the recovery of phenolic compounds and antioxidant capacity of Orthosiphon stamineus extracts. Int Food Res J. 2011;18(4):1427. doi: 10.1016/j.jep.2007.07.023.
  • 30. Dhobi M, Mandal V, Hemalatha S. Optimization of microwave assisted extraction of bioactive flavonolignan-silybinin. J Chem Metrol. 2009;3(1):13-23. doi: 10.1016/S0255-2701(02)00037-5.
  • 31. Do QD, Angkawijaya AE, Tran-Nguyen PL, Huynh LH, Soetaredjo FE, Ismadji S, et al. Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica. J Food Drug Anal. 2014;22(3):296-302. doi: 10.1016/j.jfda.2013.11.001. [PubMed: 28911418].
  • 32. Vashisth T, Singh RK, Pegg RB. Effects of drying on the phenolics content and antioxidant activity of muscadine pomace. LWT - Food Sci Technol. 2011;44(7):1649-57. doi: 10.1016/j.lwt.2011.02.011.
  • 33. Chan EWC, Lim YY, Wong SK, Lim KK, Tan SP, Lianto FS, et al. Effects of different drying methods on the antioxidant properties of leaves and tea of ginger species. Food chem. 2009;113(1):166-72. doi: 10.1016/j.foodchem.2008.07.090.
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments