Jundishapur Journal of Natural Pharmaceutical Products

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Evaluation of the Effects of Foeniculum vulgare Essence on Behavioral-Motor Disorders of Parkinson’s Disease induced by Reserpine in Ovariectomized and Non Ovariectomized Rats

Mohammad Nemati 1 , Ali Asghar Hemmati 2 , * , Hossein Najafzadeh 3 , Mohammad Taghi Mansouri 2 and Mohammad Javad Khodayar 2
Authors Information
1 Department of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Department of Pharmacology and Toxicology, Physiology Research Center, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran
Article information
  • Jundishapur Journal of Natural Pharmaceutical Products: February 2018, 13 (1); e67391
  • Published Online: February 18, 2018
  • Article Type: Research Article
  • Received: July 21, 2016
  • Revised: January 31, 2017
  • Accepted: May 3, 2017
  • DOI: 10.5812/jjnpp.67391

To Cite: Nemati M, Hemmati A A, Najafzadeh H, Mansouri M T, Khodayar M J. Evaluation of the Effects of Foeniculum vulgare Essence on Behavioral-Motor Disorders of Parkinson’s Disease induced by Reserpine in Ovariectomized and Non Ovariectomized Rats, Jundishapur J Nat Pharm Prod. 2018 ; 13(1):e67391. doi: 10.5812/jjnpp.67391.

Abstract
Copyright © 2018, Jundishapur Journal of Natural Pharmaceutical Products. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
References
  • 1. Callier S, Morissette M, Grandbois M, Pelaprat D, Di Paolo T. Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice. Synapse. 2001;41(2):131-8. doi: 10.1002/syn.1067. [PubMed: 11400179].
  • 2. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA. 2002;288(3):321-33. [PubMed: 12117397].
  • 3. Gelinas S, Martinoli MG. Neuroprotective effect of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12 cells. J Neurosci Res. 2002;70(1):90-6. doi: 10.1002/jnr.10315. [PubMed: 12237867].
  • 4. Reeves GK, Beral V, Green J, Gathani T, Bull D, Million Women Study C. Hormonal therapy for menopause and breast-cancer risk by histological type: a cohort study and meta-analysis. Lancet Oncol. 2006;7(11):910-8. doi: 10.1016/S1470-2045(06)70911-1. [PubMed: 17081916].
  • 5. Tsang AH, Chung KK. Oxidative and nitrosative stress in Parkinson's disease. Biochim Biophys Acta. 2009;1792(7):643-50. doi: 10.1016/j.bbadis.2008.12.006. [PubMed: 19162179].
  • 6. Droge W. Free radicals in the physiological control of cell function. Physiol Rev. 2002;82(1):47-95. doi: 10.1152/physrev.00018.2001. [PubMed: 11773609].
  • 7. Chen Q, Niu Y, Zhang R, Guo H, Gao Y, Li Y, et al. The toxic influence of paraquat on hippocampus of mice: involvement of oxidative stress. Neurotoxicology. 2010;31(3):310-6. doi: 10.1016/j.neuro.2010.02.006. [PubMed: 20211647].
  • 8. Beal MF. Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann N Y Acad Sci. 2003;991:120-31. [PubMed: 12846981].
  • 9. Beal MF. Oxidatively modified proteins in aging and disease1,2 1Guest Editor: Earl Stadtman 2This article is part of a series of reviews on “Oxidatively Modified Proteins in Aging and Disease.” The full list of papers may be found on the homepage of the journal. Free Radical Biol Med. 2002;32(9):797-803. doi: 10.1016/s0891-5849(02)00780-3.
  • 10. Bilska A, Dubiel M, Sokolowska-Jezewicz M, Lorenc-Koci E, Wlodek L. Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain. Neuroscience. 2007;146(4):1758-71. doi: 10.1016/j.neuroscience.2007.04.002. [PubMed: 17478054].
  • 11. Zhang Y, Dawson VL, Dawson TM. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol Dis. 2000;7(4):240-50. doi: 10.1006/nbdi.2000.0319. [PubMed: 10964596].
  • 12. Cyr M, Calon F, Morissette M, Grandbois M, Di Paolo T, Callier S. Drugs with estrogen-like potency and brain activity: potential therapeutic application for the CNS. Curr Pharm Des. 2000;6(12):1287-312. [PubMed: 10903393].
  • 13. Saunders-Pullman R, Gordon-Elliott J, Parides M, Fahn S, Saunders HR, Bressman S. The effect of estrogen replacement on early Parkinson's disease. Neurology. 1999;52(7):1417-21. [PubMed: 10227628].
  • 14. Rhodes ME, Frye CA. Estrogen has mnemonic-enhancing effects in the inhibitory avoidance task. Pharmacol Biochem Behav. 2004;78(3):551-8. doi: 10.1016/j.pbb.2004.03.025. [PubMed: 15251264].
  • 15. Aguiar RB, Dickel OE, Cunha RW, Monserrat JM, Barros DM, Martinez PE. Estradiol valerate and tibolone: effects on memory. Pharmacol Biochem Behav. 2006;85(4):689-96. doi: 10.1016/j.pbb.2006.10.023. [PubMed: 17169418].
  • 16. Ben J, Soares FM, Scherer EB, Cechetti F, Netto CA, Wyse AT. Running exercise effects on spatial and avoidance tasks in ovariectomized rats. Neurobiol Learn Mem. 2010;94(3):312-7. doi: 10.1016/j.nlm.2010.07.003. [PubMed: 20659572].
  • 17. Scott EL, Zhang QG, Han D, Desai BN, Brann DW. Long-term estrogen deprivation leads to elevation of Dickkopf-1 and dysregulation of Wnt/beta-Catenin signaling in hippocampal CA1 neurons. Steroids. 2013;78(6):624-32. doi: 10.1016/j.steroids.2012.11.004. [PubMed: 23178162].
  • 18. Sarkaki A, Badavi M, Hoseiny N, Gharibnaseri MK, Rahim F. Postmenopausal effects of intrastriatal estrogen on catalepsy and pallidal electroencephalogram in an animal model of Parkinson's disease. Neuroscience. 2008;154(3):940-5. doi: 10.1016/j.neuroscience.2008.02.022. [PubMed: 18472223].
  • 19. Mohamad RH, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, et al. Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare). J Med Food. 2011;14(9):986-1001. doi: 10.1089/jmf.2008.0255. [PubMed: 21812646].
  • 20. van Elswijk DA, Schobel UP, Lansky EP, Irth H, van der Greef J. Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry. Phytochemistry. 2004;65(2):233-41. [PubMed: 14732284].
  • 21. Choi EM, Hwang JK. Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare. Fitoterapia. 2004;75(6):557-65. doi: 10.1016/j.fitote.2004.05.005. [PubMed: 15351109].
  • 22. Namavar Jahromi B, Tartifizadeh A, Khabnadideh S. Comparison of fennel and mefenamic acid for the treatment of primary dysmenorrhea. Int J Gynaecol Obstet. 2003;80(2):153-7. [PubMed: 12566188].
  • 23. Modaress Nejad V, Asadipour M. Comparison of the effectiveness of fennel and mefenamic acid on pain intensity in dysmenorrhoea. 2006.
  • 24. Caudle WM, Colebrooke RE, Emson PC, Miller GW. Altered vesicular dopamine storage in Parkinson's disease: a premature demise. Trends Neurosci. 2008;31(6):303-8. doi: 10.1016/j.tins.2008.02.010. [PubMed: 18471904].
  • 25. Tadaiesky MT, Andreatini R, Vital MA. Different effects of 7-nitroindazole in reserpine-induced hypolocomotion in two strains of mice. Eur J Pharmacol. 2006;535(1-3):199-207. doi: 10.1016/j.ejphar.2006.02.004. [PubMed: 16546164].
  • 26. Faria RR, Abilio VC, Grassl C, Chinen CC, Negrao LT, de Castro JP, et al. Beneficial effects of vitamin C and vitamin E on reserpine-induced oral dyskinesia in rats: critical role of striatal catalase activity. Neuropharmacology. 2005;48(7):993-1001. doi: 10.1016/j.neuropharm.2005.01.014. [PubMed: 15857626].
  • 27. Fernandes VS, Santos JR, Leao AH, Medeiros AM, Melo TG, Izidio GS, et al. Repeated treatment with a low dose of reserpine as a progressive model of Parkinson's disease. Behav Brain Res. 2012;231(1):154-63. doi: 10.1016/j.bbr.2012.03.008. [PubMed: 22446059].
  • 28. Malini T, Vanithakumari G, Megala N, Anusya S, Devi K, Elango V. Effect of Foeniculum vulgare Mill. seed extract on the genital organs of male and female rats. Indian J Physiol Pharmacol. 1985;29(1):21-6. [PubMed: 4055014].
  • 29. Kim SU, de Vellis J. Microglia in health and disease. J Neurosci Res. 2005;81(3):302-13. doi: 10.1002/jnr.20562. [PubMed: 15954124].
  • 30. Honari N, Pourabolli I, Shamsizadeh A, Amin F, Allatavakoli M. Effect of Vitex Agnus-Castus Extract on Learning and Memory in Ovariectomized Rats. J Mazandaran Univ Med Sci. 2012;22(93):2-10.
  • 31. Moghaddam HF, Khodayar MJ, Abarghouei SM, Ardestani MS. Evaluation of the role of striatal cannabinoid CB1 receptors on movement activity of parkinsonian rats induced by reserpine. Saudi Pharm J. 2010;18(4):207-15. doi: 10.1016/j.jsps.2010.05.003. [PubMed: 23960729].
  • 32. Ramirez AD, Liu X, Menniti FS. Repeated estradiol treatment prevents MPTP-induced dopamine depletion in male mice. Neuroendocrinology. 2003;77(4):223-31. doi: 10.1159/000070277. [PubMed: 12766322].
  • 33. Jeon S, Kim YJ, Kim ST, Moon W, Chae Y, Kang M, et al. Proteomic analysis of the neuroprotective mechanisms of acupuncture treatment in a Parkinson's disease mouse model. Proteomics. 2008;8(22):4822-32. doi: 10.1002/pmic.200700955. [PubMed: 18942673].
  • 34. Wang CC, Lin JD, Chen LL. Personal health maintenance: the perspective of traditional Chinese medicine. Hu li za zhi J Nurs. 2010;57(2):10-5.
  • 35. Ferger B, Leng A, Mura A, Hengerer B, Feldon J. Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum. J Neurochem. 2004;89(4):822-33. doi: 10.1111/j.1471-4159.2004.02399.x. [PubMed: 15140182].
  • 36. Qu N, Wang L, Liu ZC, Tian Q, Zhang Q. Oestrogen receptor alpha agonist improved long-term ovariectomy-induced spatial cognition deficit in young rats. Int J Neuropsychopharmacol. 2013;16(5):1071-82. doi: 10.1017/S1461145712000958. [PubMed: 22999489].
  • 37. Sandhir R, Sethi N, Aggarwal A, Khera A. Coenzyme Q10 treatment ameliorates cognitive deficits by modulating mitochondrial functions in surgically induced menopause. Neurochem Int. 2014;74:16-23. doi: 10.1016/j.neuint.2014.04.011. [PubMed: 24780430].
  • 38. Subramaniam SR, Chesselet MF. Mitochondrial dysfunction and oxidative stress in Parkinson's disease. Prog Neurobiol. 2013;106-107:17-32. doi: 10.1016/j.pneurobio.2013.04.004. [PubMed: 23643800].
  • 39. Nakisa H, Ayoobi F, Ehsani V, Akramian M, Khajehasani F, Rahmani M, et al. Assessment of Foeniculum Vulgare L. methanolic extract effect on a model of Parkinson s disease. induced by ICV injection of 6-hydroxydopamin in female rats, using behavioral tests. J Birjand Univ Med Sci. 2015;21.
  • 40. Abilio VC, Vera JJ, Ferreira LS, Duarte CR, Carvalho RC, Grassl C, et al. Effects of melatonin on orofacial movements in rats. Psychopharmacology (Berl). 2002;161(4):340-7. doi: 10.1007/s00213-002-1081-7. [PubMed: 12073160].
  • 41. Gluck MR, Zeevalk GD. Inhibition of brain mitochondrial respiration by dopamine and its metabolites: implications for Parkinson's disease and catecholamine-associated diseases. J Neurochem. 2004;91(4):788-95. doi: 10.1111/j.1471-4159.2004.02747.x. [PubMed: 15525332].
  • 42. Arora V, Chopra K. Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model. J Affect Disord. 2013;151(3):1041-52. doi: 10.1016/j.jad.2013.08.032. [PubMed: 24126118].

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