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BENEFICIAL EFFECTS OF SOYPROTEIN ISOFLAVONES ON LIPID AND BLOOD GLUCOSE CONCENTRATIONS IN TYPE 2 DIABETIC SUBJECTS

AUTHORS

H.B Shahbazian 1 , * , R Amani 2 , J Siadatan 2 , H Shahbazian 2 , M Latifi 2 , A Ahmadzadeh 2 , M Haghighizadeh 2

1 Endocrine Department, Golestan Hospital, Ahwaz Jundishapur University of Medical Sciences, Hjb_shahbazian@yahoo.com

2 School of Paramedical Sciences, Ahwaz Jundishapur University of Medical Sciences

How to Cite: Shahbazian H, Amani R, Siadatan J, Shahbazian H, Latifi M, et al. BENEFICIAL EFFECTS OF SOYPROTEIN ISOFLAVONES ON LIPID AND BLOOD GLUCOSE CONCENTRATIONS IN TYPE 2 DIABETIC SUBJECTS , Jundishapur J Nat Pharm Prod. Online ahead of Print ; 1(1):48-52.

ARTICLE INFORMATION

Jundishapur Journal of Natural Pharmaceutical Products: 1 (1); 48-52
Article Type: Research Article
Received: February 10, 2006
Accepted: November 23, 2005

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Abstract

Consumption of soyprotein has recently been shown to improve the blood lipid levels in  non-diabetic subjects. The purpose of this study was to evaluate if a dietary soyprotein isoflavones affects lipid and blood glucose levels in type 2 diabetic subjects. Twenty six type 2 diabetic patients who had refferd to Ahvaz Jundishapour University Diabetes Center, due to uncontrolled diabetes, participated in this study. They completed a trial of dietary supplementation with 25gr/day of a processed defeated meal containing 12 gr soyprotein and about 50mg isoflavones, for 3 months. FBS, HbA1C, serum total cholesterol, triglyceride, HDL and LDL-C and patients, weight and blood pressure were checked before soyprotein consumption and monthly thereafter. There were significant differences in mean FBS (153±50 versus 178±60, P< 0.015), HbA1C (8.8 ± 1.4 versus 9.6 ± 1.7 percent, P<0.001), triglycerides concentration (229 ± 113 versus 267 ± 149 P<0.008) and total cholesterol (196 ± 41 versus 207 ± 42, P<0.002) before and after three months consumption of soyprotein isoflavones.There were no significant changes in HDL and LDL-C cholesterol levels, blood pressure and weight.

Keywords

Blood glucose, Diabetes type 2, Soyprotein and isoflavones, Blood lipids.

© 0, Jundishapur Journal of Natural Pharmaceutical Products. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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