Cite Score:
1.07
CITE SCORE SCOPUS

TREATMENT OF OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS: SODIUM FLUORIDE OR CALCITONIN

AUTHORS

K Mowla 1 , *

1 Department of Internal Medicine, Ahwaz Jundishapur University of Medical Sciences

How to Cite: Mowla K. TREATMENT OF OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS: SODIUM FLUORIDE OR CALCITONIN, Jundishapur J Nat Pharm Prod. 2006 ; 1(1):e74294.

ARTICLE INFORMATION

Jundishapur Journal of Natural Pharmaceutical Products: 1 (1); e74294
Published Online: December 05, 2006
Article Type: Research Article
Received: September 12, 2005
Accepted: July 05, 2004

Crossmark

CHEKING

READ FULL TEXT
Abstract

Historical controversy and lack of controlled clinical trial study comparing the effects of sodium fluoride and calcitonin therapies in osteoporosis of patients with RA made us to conduct this study to clarify which one of the above treatments would be more useful and effective in the treatment of osteoporosis.

From subjects who turned to Ahwaz Rheumatoid Arthritis Clinic during 2000, all women who met the American College of Rheumatology (ACR) 1987 criteria for RA (7), WHO 1994 criteria for osteoporosis (8) and signed the written consent were enrolled into the study. Considering these inclusion criteria, 70 women were enrolled into the study. They were randomized into two groups. Age, BMI (body mass index) and BMD (bone mineral density) were the adjusted variables during randomization. Thirty-four patients were treated with 20 mg sodium fluoride daily and 36 patients with 200 units nasal calcitonin per day. All patients were treated for 12 months.

Patients who received Fluoride showed significant higher BMD in femoral neck (0.74 vs. 0.65, p<0.01) and in lumbar spine (0.90 vs. 0.79, p<0.05) than who received calcitonin after 12 months of therapy.

Keywords

Osteoporosis Sodium Fluoride Calcitonin

© 2006, Jundishapur Journal of Natural Pharmaceutical Products. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

Full text is available in PDF.

COMMENTS

LEAVE A COMMENT HERE: