DISTRIBUTION MODEL OF SERUM LIPOPROTEIN (A) CONCENTRATION IN A HEALTHY IRANIAN POPULATION LIVING IN KHUZESTAN PROVINCE, IRAN. 2004.

AUTHORS

M Taha Jalali 1 , *

1 Department of Medical Laboratory Sciences, Para-medical Faculty, Ahwaz Jundishapur University of Medical Sciences, [email protected], Iran

How to Cite: Taha Jalali M. DISTRIBUTION MODEL OF SERUM LIPOPROTEIN (A) CONCENTRATION IN A HEALTHY IRANIAN POPULATION LIVING IN KHUZESTAN PROVINCE, IRAN. 2004., Jundishapur J Nat Pharm Prod. Online ahead of Print ; 2(2):111-115.

ARTICLE INFORMATION

Jundishapur Journal of Natural Pharmaceutical Products: 2 (2); 111-115
Article Type: Research Article
Received: November 12, 2007
Accepted: December 9, 2007

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Abstract

Based on many epidemiologic studies, lipoprotein (a) [Lp(a)] with its peculiar structural properties  was proposed as independent, risk factor for cardiovascular and thrombotic cerebral events. Since, genetic effect plays a paramount role in determining the final serum concentration, the reference serum concentration for this particle exhibits a wide variation among different population and even within a family. In order to prevent its pathologic effect which has been related to its high serum concentration it is a prerequisite to determine its serum concentration distribution model in a particular population before any therapeutic measure is arranged. To accomplish this goal a group of 350 healthy volunteers living in southern province of Khuzestan, Iran, were analyzed for their Lp (a) serum concentration employing and isoform- insensitive ELISA technique. The obtained result showed skewed distribution toward lower concentration ranging from 3 to 53 mg/dL with mean, median and standard deviation as 14.42, 12.0 and 8.46 mg/dL.

 

Keywords

Lipoprotein (a), Healthy population, Skewed distribution, Reference range.

© 0, Jundishapur Journal of Natural Pharmaceutical Products. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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